Tyrosinase Inhibitor in Fortner's Amelanotic and Melanotic Malignant Melanoma*
نویسندگان
چکیده
منابع مشابه
Subungual amelanotic malignant melanoma.
We report a 61-year-old, male patient complaining from prolonged lesion on his great toe that has been previously treated surgically. Histopathological examination of toenail specimen revealed the presence of nests of atypical tumor cells that led to the diagnosis of amelanotic malignant melanoma. Four years ago, he was diagnosed as gout due to extreme erythema and edema in the same toe. He has...
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We present the case of a 74-year-old white female admitted to the Department of Dermatology because of a tumor in the IV-V interdigital area of her right foot. A crimson, dome-shaped tumor with a granular, spongy surface (diameter 4 cm) had developed over a period of about 3 months. The biopsy, stained with H and E, revealed an anaplastic malignant tumor. Additional immunochemical staining with...
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Amelonotic malignant melanoma; Sinonasal cavity; Nasal polyposis; Immunocytochemistry Abstract Malignant melanoma involving mucosal surface of the head and neck region is rare. Malignant melanoma involving the nasal cavity is even rarer and accounts for less than 1% of cases. Prognosis is generally poor with unpredictable outcome. Regional and distant metastasis is common at presentation. We pr...
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MATERIALS AND METHODS Murine malignant melanoma (B16) cells tolerant to 10 and 30 pg of BrdU per ml were maintained for more than one year in culture medium lacking the analog. The analog-containing environment was also eliminated by the injection of cells at several subcultures into host animals. Cells withdrawn from BrdU retained the enlarged, flattened, nonpigmented morphology that is charac...
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Four months previously, the patient had presented to another clinic with a painless mass in the right parotid region. There was no skin lesion at that time. A fine needle biopsy was performed. The pathology results indicated that the mass was a malignant tumor, and the surgeon suggested total parotidectomy; however, the patient was afraid of surgery and did not seek medical attention again unti...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 1967
ISSN: 0022-202X
DOI: 10.1038/jid.1967.50